Quercetin 3,5,7,3’,4’-pentamethyl ether from Kaempferia parviflora directly and effectively activates human SIRT1

【2021】

 

Mimin Zhang¹ , Peng Lu¹ , Tohru Terada^2,3, Miaomiao Sui¹ , Haruka Furuta^1,4, Kilico Iida^1,5, Yukie Katayama¹ , Yi Lu¹ , Ken Okamoto¹ , Michio Suzuki¹ , Tomiko Asakura¹, Kentaro Shimizu^2,3, Fumihiko Hakuno^1,4, Shin-Ichiro Takahashi^1,4, Norimoto Shimada⁶, Jinwei Yang⁶ , Tsutomu Ishikawa⁶ , Jin Tatsuzaki⁶ , Koji Nagata^1,3

 

1 Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo
2 Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo
3 Agricultural Bioinformatics Research Unit, Graduate School of Agricultural and Life Sciences, The University of Tokyo
4 Department of Animal Resource Sciences, Graduate School of Agricultural and Life Sciences, The University of Tokyo
5 Division of Food and Nutrition, Graduate School of Human Sciences, Kyoritsu Women’s University
6 Tokiwa Phytochemical Co. Ltd.

 

Communications Biology (2021)

URL : https://www.nature.com/articles/s42003-021-01705-1