Extraction fraction containing polymer condensation tannin obtained from ephedra extract or ephedrine alkaloids-free ephedra herb extract, and method of producing the same and use thereof

Title of the Invention

Extraction fraction containing polymer condensation tannin obtained from ephedra extract or ephedrine alkaloids-free ephedra herb extract, and method of producing the same and use thereof

Patent Holder

The Kitasato Institute
Director-General of the National Institute of Health Sciences

Matsuyama University

Tokiwa Phytochemical Co., Ltd.

Zeria Pharmaceutical Co Ltd

 

Inventor

Tsutomu Shimada, Jinwei Yang, Yuka Koike

Patent No.

JP 7544322

Filing Date

2022. 12. 28

Registration Date

2024. 8. 26

Abstract

The present invention relates to an extract fraction containing polymeric condensed tannins with a weight-average molecular weight of 45,000 or more derived from Ephedra extract or from ephedrine alkaloids-free Ephedra Herb extract (EFE), a method for producing the same, and a pharmaceutical composition containing the extract fraction. The pharmaceutical composition of the present invention is useful as an anticancer drug, an antimetastatic drug, and an anti-influenza virus drug.