Scientific Papers_2022

HPLC analysis of ammonium glycyrrhizate listed in the European, United States, and Japanese Pharmacopoeias under reported and modifed　conditions: revision of the peak assignment for 18α‑glycyrrhizin in the European and United States Pharmacopoeias

【2022】

Kazuaki Kamata1,3 · Jin Tatsuzaki1· Tsutomu Ishikawa1 · Ryoko Arai2
· Takashi Hakamatsuka2,4 · Nahoko Uchiyama2

1) Tokiwa Phytochemical Co., Ltd
2) National Institute of Health Sciences
3) Present Address: Gunma University Center for Food Science and Wellness

4) Present Address: Department of Pharmaceutical Sciences,

Nihon Pharmaceutical University

Journal of Natural Medicines

77:202-206 (2023)

Corosolic acid improves glucose and insulin responses in middle-aged men with impaired fasting glucose: A randomized, double-blinded, placebo-controlled crossover trial

【2022】

Masanobu Hibi1), Yuji Matsui2), Sachiko Niwa2), Sachiko Oishi1), Aya Yanagimoto1), Takahiro Ono3), Tohru Yamaguchi2)

1) Biological Science Research Laboratories, Kao Corporation
2) Health & Wellness Products Research Laboratories, Kao Corporation
3) Ueno-Asagao Clinic

Journal of Functional Foods

97 105256 (2022)

Assessment of in vitro, in vivo, and Clinical Safety of SIRTMAX® a Standardized Kaempferia parviflora Rhizome Extract

【2022】

Chin Piow Wong 1), Yukiko Kobayashi 1), Jinwei Yang 1)

1) Tokiwa Phytochemical Co., Ltd.

Jpn Pharmacol Ther

50 (10) 1889-1899 (2022)

Characterization and Utilization of Disulfide-Bonded SARS-CoV-2 Receptor Binding Domain of Spike Protein Synthesized by Wheat Germ Cell-Free Production System

【2022】

Yutaro Yamaoka1)2), Sundararaj Stanleyraj Jeremiah1), Rikako Funabashi1), Kei Miyakawa1), Takeshi Morita1), Yusaku Mihana1)2), Hideaki Kato3), Akihide Ryo1)

1) Department of Microbiology, Yokohama City University Graduate School of Medicine
2) Life Science Laboratory, Technology and Development Division, Kanto Chemical Co., Inc.
3) Infection Prevention and Control Department, Yokohama City University Hospital

Viruses

14 (7) 1461 (2022)

The effect of food containing Apocynum venetum leaf extract on daytime sleepiness, stress, in daily life, and concentration —A randomized, double—blind, placebo—controlled, crossover study—

【2022】

Kohei Fujiki1), Yuki Hirashima1), Takatoshi Ogami1), Akira Takano1), Tomoyasu Kamiya1), Kinya Takagaki1), Yoshitaka Iwama2)

1) Toyo Shinyaku Co., Ltd.
2) Nihonbashi Cardiology Clinic

Jpn Pharmacol Ther　
50 (4) 733-741 (2022)

Successful Commercialization of an Anti-Aging Ingredient Based on Advanced Research: Latest Advancement of SIRTMAX®( Kaempferia parviflora extract) in SIRT1 Activation and Clinical Study

【2022】

Jin Tatsuzaki

Tokiwa Phytochemical Co., Ltd.

International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM) 2022（HongKong）

11 August 2022 ～ 12 August 2022
※Onsite & Online Hybrid

”Oral health first” The base of health start from mouth. Oral care with tokiwa’s “LAURESH®”

【2022】

Ayumi Horie, Yukiko Kobayashi

Tokiwa Phytochemical Co., Ltd.

FOOD STYLE 21
26(7) 58-60 (2022)

Anti-skin Aging Activities of Sideritis scardica and 3 Flavonoids With an Uncommon 8-Hydroxyl Moiety

【2022】

Fumiaki Sato1), Chin Piow Wong2), Kaito Furuya1), Chikako Kuzu1), Ryousuke Kimura1), Tomoha Udo1), Haruno Honda2), Jinwei Yang2)

1) Laboratory of Analytical Pathophysiology, Hoshi University
2) Tokiwa Phytochemical Co., Ltd.

Natural Product Communications
17(5) 1-10 (2022)